Kurbanlarını kan emen yaratıklara dönüştüren ve hızla yayılan bir hastalık, insanlığın geleceği için verilen savaşta iki yakın arkadaşı birbirine düşürür.
Dr. Luther Swann, enters a world of horror when a virus is released in ice melting due to climate change. This disease transforms his best friend, Michael Fayne, into a murderous predator who feeds on human blood when he has the hunger. As the disease spreads and more people are transformed, society fractures into camps putting normal people against the growing number of these vampires. Swann race against time to understand what's happening, while Fayne rises to become the powerful underground leader of the vampires until revolution and a new election.